Conversely, loss of miR-34a function resulted in increased numbers of mature B-cells accompanied by modestly elevated amounts of FOXP1. As confirmation, recently Carig et al. [96] revealed that the malignant transformation of Mucosa associated lymphoid tissue (MALT) lymphoma to gastric Diffuse Large B-Cell Lymphoma (DLBCL) is linked to overexpression of FOXP1 due to the repression of the tumor suppressor miR-34a mediated by the aberrant expression of MYC in high-grade transformation of gastric B-cell lymphoma. This evidence concerns the gene FOXP1 and diffuse large B-cell lymphoma.