TP53 and neoplasm: Control of transition from proB- to preB-cells [50,51].Down-regulation of c-MYB, expression [18,51]: interaction important for oncogenesis and (or) tumor progression [52,53,54].Regulation of the NK and iNKT cell development [55].Reduction of phosphorylated AKT (ser473/4) levels and increasing Bim and TP53 by directly down-regulating the DKC1 and AKT2 expression [56].