Several polymorphisms have been associated with higher prevalence of arterial hypertension; there are 2 polymorphisms in the Angiotensin Converting Enzyme (ACE) and Angiotensin Converting Enzyme 2 (ACE2) that lead to elevate circulating Ang II levels (Giner et al., 2000; Di Pasquale et al., 2004; Fan et al., 2007). The gene discussed is ACE2; the disease is Hypertension.