The telomere-associated SNPs in TERC, TERT, OBFC1, and RTEL1 are near (8-150kb from) SNPs strongly associated with melanoma risk (rs12696304 in TERC, P = .0001; rs455433 in TERT, P = 2.26x10-16; rs2995264 in OBFC1, P = 7.10x10-6; rs75691080 in RTEL1, P = 1.02x10-6) (Supplementary Figure 1, available online). This evidence concerns the gene TERC and melanoma.