This also indicated that the expression of CHT1, VAChT, BDNF and CREB mRNAs in the hippocampus in rats treating acupuncture stimulation of GV20, but not of TE4 or the tail, restored memory impairment-related cholinergic function, and activated BDNF and CREB mRNAs expression. Here, BDNF is linked to memory impairment.