In an in vivo experiment with a tumour xenograft model that used LoVo cells, qRT-PCR and Western blot analysis found that c-Myb expression at the mRNA and protein levels decreased in the miR-150 mimic-treatment group and increased in the miR-150 inhibitor-treatment group, relative to the controls (Fig.3D and F). This evidence concerns the gene MYB and neoplasm.