To our interests, Bao et al. [17] identified nucleolin as a candidate biomarker for diagnosis of HCC by quantitative proteomic analysis of a paired human liver healthy versus carcinoma cell lines with the same genetic background; Meng et al. [18] further found that the downregulation of nucleolin expression may inhibit the growth of HCC cells in vitro. The gene discussed is NUCLEOLIN; the disease is hepatocellular carcinoma.