To thoroughly compare double mutant vs single c-myc transgenic mice tumors, we thus analyzed gene expression profiles of 8 IgA-expressing type I lymphomas (including 4 type Ia and 4 type Ib tumors) from double mutant mice compared to 8 IgM-expressing c-myc3′RR lymphomas (including 4 “BL-like” and 4 anaplastic lymphomas). This evidence concerns the gene CD40LG and lymphoma.