In the present case the patient visited three tertiary hospitals, underwent more than 10 gastroscopies, three ileo-colonoscopies, several enteroscopies, bone marrow aspiration, various mutational analyses and many other examinations, until clinical signs to search for gastrointestinal allergy were recognized adequately and in detail, such as atopic status, persistent eosinophilia and elevated serum IgE levels. Here, IGHE is linked to gastrointestinal allergy.