An important target for the detection and monitoring of the recurrence of colon cancer is the human carcinoembryonic antigen (CEA, CEACAM5), a key member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) and a GPI-anchored cell surface glycoprotein that has been shown to be useful as a tumor-associated antigen and serum marker [3], [4]. This evidence concerns the gene CEACAM5 and colonic neoplasm.