The mutant homozygous genotype for TLR3 rs3775291 was found significantly less frequently among TBE patients in both the combined cohort of children and adults (n = 232) and the overall combined cohort of TBE cases (n = 331), compared to the combined control cohort (p = 0.02 and p = 0.025, respectively) (Table 4). Here, TLR3 is linked to tick-borne encephalitis.