Plasma concentrations of cytokines in patients with CLL: As shown in Table-II, plasma concentrations of IL-17A, IL-23 and IL-6 in the untreated group (IL-17: 3.23 (1.33-17.9) pg/ml; IL-23: 78.06 (0.79-236.73) pg/ml; IL-6: 9.28 (0.42-511.24) pg/ml) increased significantly compared to the healthy control group (IL-17: 0.71 (0.39-9.94) pg/ml; IL-23: 18.03 (13.69-27.16) pg/ml; IL-6: 0.77 (0.53-1.06) pg/ml; p<0.05). The gene discussed is IL6; the disease is B-cell chronic lymphocytic leukemia.