Levels of TPA and IL-6 were assessed in the sera of the blood of 30 patients with breast cancer, with mean age ±SD of (46.91±8.65 years), after receiving six cycles of chemotherapy and compared to their values in another 30 breast cancer patients with mean age ±SD of (45.43±7.99 years), 3 weeks postoperative and just before receiving the first cycle of chemotherapy. The gene discussed is IL6; the disease is breast cancer.