There are conflicting reports of either positive or negative associations of adiponectins levels with mood disorder (Yilmaz, 2008; Zeman et al., 2009; Jeong et al., 2012; Wilhelm et al., 2013), or no changes in patients with major depressive disorder or with antidepressants (Lehto et al., 2010; Jeong et al., 2012). Here, ADIPOQ is linked to mood disorder.