CEP290 and Atrophy: Interestingly other tight relationships between BTBR coherently-regulated factors were found, e.g., myelin-associated activity [Lancl1 (LanC bacterial lantibiotic synthetase component C)-like 1 and Ermn] and inherited neuronal atrophy and impairment [Prrt2 (proline-rich transmembrane protein 2) and Cep290 (centrosomal protein 290)] (Figure 6D).