KDR and neoplasm: Visualization of tissue samples (on day 17 after the first injection) using TUNEL assay demonstrated a significantly higher number of apoptotic cells in tumors from VEGFR2 cRGD-siRNA1 or cRGD-siRNA2 treated mice, when compared to the tumor tissues prepared from the control VEGFR2 cRAD-siRNA2 or saline treated animals (Figure 5D).