The expression of the mature form of SREBP-1c (mSREBP-1c), SCD-1 and FAS were increased in T2D mice compared to non-diabetic mice (1.00±0.16 vs. 0.80±0.06 of CH mice; 1.00±0.29 vs. 0.51±0.19 of CH mice, p<0.05; 1.00±0.14 vs. 0.88±0.15 of CH mice, all n = 5–8, respectively). This evidence concerns the gene SREBF1 and type 2 diabetes mellitus.