NPY and vitiligo: NPY exon 2 (+1128; T/C) and promoter (−399; T/C) polymorphisms when compared between generalized (GV) and localized (LV) vitiligo patients (Table 2), the observed genotype frequencies for these polymorphisms in GV and LV patients with respect to unaffected controls were found to be significantly different (p<0.0001, p = 0.0002 and p = 0.029, p<0.0001).