SLCO1B1 and myopathy: Indeed, the data supporting the association between a variant (rs4149056; T521C; Val174Ala) in SLCO1B1 (the gene encoding the solute carrier organic anion transporter family member 1B1) and simvastatin-induced myopathy was so strong that the Clinical Pharmacogenetics Implementation Consortium (CPIC) wrote guidelines for simvastatin therapy based on SLCO1B1 T521C genotype [13].