This autonomic dysfunction was accompanied by electrocardiographic changes associated with mild diffuse inflammatory infiltration of mononuclear cells as well as fibrosis and hypertrophy in the atrial and ventricular myocardium and the elevation of IFN-γ and IL-10 in the blood serum of wild-type and untreated chagasic C57BL/6j mice, which confirms the presence of chronic myocarditis six months following infection with T. cruzi. The gene discussed is IFNG; the disease is infection.