Higher concentrations of plasminogen were found in Guillain-Barré syndrome (GBS) (median = 1.28 ng/μl (25th to 75th interquartile range (IQR) = 0.66 to 1.59), n = 15) as compared to multiple sclerosis (MS) (median = 0.3 ng/μl (IQR = 0.16 to 0.61), n = 19) and noninflammatory neurological diseases (NINDs) (median = 0.27 ng/μl (IQR = 0.18 to 0.35), n = 8) (P < 0.0001, one-way ANOVA). This evidence concerns the gene PLG and nervous system disorder.