Comprehensive analysis of genomic aberrations in cervical tumors allowed to identify, besides the previously characterized mutations in TP53 and PIK3CA genes, unknown mutations in MAPK1, HLA-B, EP300, FBXW7, NFE2L2, and ERBB2 genes in squamous cell carcinoma and somatic mutations of ELF3 (13%) and CBFB (8%) genes in adenocarcinomas [18]. The gene discussed is PIK3CA; the disease is adenocarcinoma.