Furthermore, a series of review articles has strongly suggested that PANDER could potentially be implicated in the onset or progression of type 2 diabetes (T2D) (Wang et al., 2012; Wilson et al., 2011; Yang and Guan, 2013), yet the impact of this gene within well-established models of T2D or insulin resistance has not been generated. The gene discussed is FAM3B; the disease is type 2 diabetes mellitus.