The morphology of the microglial cells further indicated that these cells, whether or not they colabeled for PCNA, were minimally activated, particularly when compared to the morphology of microglia in Parkinson's disease patients [57, 67, 68] or to the hyper-ramified and rod-like Iba1+ morphologies observed, for example, in pediatric epilepsy [69]. The gene discussed is AIF1; the disease is Parkinson disease.