SOAT1 and age-related macular degeneration: According to Lin et al., all the above cytokines are novel agent (genes) associated with AMD pathogenesis and candidate marker of inflammatory events in the outer retina, and modulating their activity associated with specific pathways (NF-jB and JAK-STAT pathways) may be new therapeutic strategy to limit RPE dysfunction and photoreceptor loss in the course of AMD [39].