After adjustment for age, education level, number of years of completed education, illness duration, total PANSS score, depression severity in PANSS and chlorpromazine equivalent, there was a trend level association of hsCRP and statistically significant association of IL-6 with lower scores on immediate recall span assessed by RAVLT (total score summed across 1st through fifth trial) (β = −0.13 95 %CI −0.26–0.01, p = 0.06; β = −0.05, 95 %CI −0.10–0.01, p = 0.04, respectively). Here, IL6 is linked to depressive disorder.