The miR-34 family is composed of miR-34a,miR-34b and miR-34c and mediates tumour cell activities through cell cycle arrest, apoptosis or senescence, and metastasis 34–36, depending on its targets, such as the oncogenes BCL-2,c-MYC and c-MET8,10,35. The gene discussed is BCL2; the disease is neoplasm.