NR4A1 and breast cancer: Importantly, a significant increase in hormone receptor positive breast cancer was observed with a family history of lung cancer (OR: 3.37, 95% CI: 1.45 – 7.82); however, subjects with a family history of lung cancer did not show a significant increase in hormone receptor negative breast cancer (OR: 1.30, 95% CI: 0.33 – 5.14).