To determine the impact of helminth infections on the circulating levels of the prototypical Th1 and Th17 cytokines as well as regulatory cytokines, we measured the levels of IFN-γ, TNF-α, IL-2, IL-17A, IL-17F,IL-22, IL-10 and TGFβ in the plasma of three groups of individuals with active TB - FIL/TB, STR/TB or TB alone. The gene discussed is TNF; the disease is helminthiasis.