In brief, the putative target fulfilled the following criteria: (1) it was detected as putative target in all three databases, (2) it has been reported to play a role in B-cell development and was found overexpressed in MCL, other NHL subtypes or other cancers, (3) it was a positive regulator that led to activation of signaling pathways that were activated in MCL (e.g. NF-kB, ERK and AKT) or in other cancers, and (4) the target had a typical 7-8mer (8mer, 7mer-m8, 7mer-A1) match to the miR-155-3p seed region as predicted by the databases. Here, AKT1 is linked to mantle cell lymphoma.