Receptor tyrosine kinases constitute a large family of receptors that regulate thecell cycle and are often activated in MM.(74) Among receptor tyrosine kinases, EGFR was detected in 44% of all casesof MPM.(75) In addition, VEGF is expressed in MM and is associated with decreasedpatient survival.(76) In addition, insulin-like growth factor and its receptor are also activein MM.(77). Here, EGFR is linked to Miyoshi myopathy.