Some studies have attempted to relate increasedlevels of some endothelial markers, such C-reactive protein and fibrinogen, toCOPD.(7,8) One study reported increased vWF levels in COPD patients duringexacerbations.(10) However, the role of this marker in COPD during the stable phase of thedisease has yet to be established. Here, VWF is linked to chronic obstructive pulmonary disease.