Alcohol dehydrogenase transcripts were upregulated in the iron deficiency + Hb condition; they included aldehyde-alcohol dehydrogenase 2 (EHI_024240; a 2.3-fold increase), which known to be involved in the internalization of human transferrin [47] and is regulated by iron [3]. This evidence concerns the gene AKR1A1 and Iron deficiency anemia.