IL2 and diabetes mellitus: In a model of diabetes, when islet-specific Tconv cells were transferred alone, they induced diabetes, but when the same Tconv cells were co-transferred with islet-specific Treg cells, they induced disease protection by boosting Treg cell expansion and suppressive function.38 Tconv cells may act on Treg cell proliferation via production of IL-2, but their role in the generation of tTreg cells has never been described.