LPAR3 and cancer: Although low levels of LPA3 were observed in all breast tissues, the cancer tissues exhibited a greater expression of LPA3 than did normal (0.05 ± 0.023 vs. 0.02 ± 0.002, P < 0.001) or benign-disease tissues (0.05 ± 0.023 vs. 0.03 ± 0.002, P < 0.001) (Fig. 1d).