As expected, breast cancer cell lines (MCF-7, T47D, MDA-MB-231, and MDA-MB-157) expressed more LPA3 than normal immortal cells (MCF-10A and MCF-12A), and the highest expression of LPA3 was detected in the TNBC cells (MDA-MB-231 and MDA-MB-157) (Fig. 3b, c). The gene discussed is LPAR3; the disease is breast carcinoma.