On individual correlations using the Spearman coefficient r, the following parameters correlated significantly with afamin concentrations: BMI (r = 0.231, p = 0.02), waist/hip ratio (r = 0.310, p = 0.019), fasting insulin (r = 0.313, p = 0.002), LDL cholesterol (r = 0.257, p = 0.013), HOMA Index (r = 0.310, p = 0.002), and triglycerides (r = 0.372, p = 0.001) as the only criterion of metabolic syndrome. This evidence concerns the gene INS and metabolic syndrome.