However, on multivariable linear regression including as independent variables selected parameters that significantly correlated with afamin (BMI, LDL cholesterol, triglycerides, HOMA Index and fasting insulin) only triglyceride concentration was seen to be an independent predictor of afamin concentration (β coefficient = 0.271, p = 0.019, Durbin-Watson 1.468).Finally, we compared median afamin concentrations between those with and without diagnosed metabolic syndrome, independent of the presence of PCOS. The gene discussed is AFM; the disease is polycystic ovary syndrome.