In contrast, normal bladder and HUVEC cell lines showed only marginal expression for IL-4Rα and IL-13Rα1 chains and undetectable IL-2RγC. Overexpression of IL-4Rα was also demonstrated by IHC in tumors but not in normal bladder samples confirming the data in the BC cell lines. The gene discussed is IL13RA1; the disease is breast cancer.