For instance, as shown in the recent study (Smith et al., 2013), a frequent promoter variant rs6311 of the HTR2A [5-hydroxytryptamine (serotonin) receptor 2A] gene, widely implicated in human neuropsychiatric disorders and significant in the meta analysis in the Schizophrenia Gene database (Allen et al., 2008), decreases usage of an upstream transcription site encoding a longer 5′UTR with greater translation efficiency. The gene discussed is HTR2A; the disease is schizophrenia.