We found two new occurrences of PRKCA (protein kinase C, alpha) fusions in lung squamous cell carcinoma and three PRKCB (protein kinase C, beta) fusions in lung squamous cell carcinoma, lung adenocarcinoma and low-grade glioma (Fig. 1, Supplementary Fig. 9a,c). This evidence concerns the gene PRKCA and central nervous system cancer.