TP53 and non-Hodgkin lymphoma: In the pathology-stratified or grade-stratified analyses, significantly elevated NHL risk was found in the TP53 Arg/Pro and Pro/Pro genotypes carriers only in BCL cases (OR = 2.02, 95% CI = 1.31–3.10, P = 0.001) and cases with grade 3 or 4 disease (OR = 2.46, 95% CI = 1.50–4.05, P<0.001) (Table 3).