CHI3L1 and cardiovascular disorder: These CHI3L1 SNPs included rs10399805 (−247, G/A) and rs4950928 (−131, C/G) in the promoter region, and rs880633 (+2950, T/C) in exon 5 etc. However, Thomsen et al., also using the Danish population in the international MONICA (MONItoring trends and determinants of CArdiovascular disease) project, demonstrated that 12SNPs were associated with serum YKL-40 levels [9].