MKI67 and non-small cell lung carcinoma: Multivariate Cox regression analysis showed NEK2 expression was an independent prognostic factor for overall survival in patients with NSCLC (hazard ratio, 2.234; 95% confidence interval, 1.104–4.523; P=0.025), which was an improvement on the expression of Mcm7 (P=0.034) and Ki67 (P=0.026).