CAV1 and non-small cell lung carcinoma: In addition, Ho et al (105) identified that Cav-1 expression significantly correlates with drug resistance and poor prognosis in advanced non-small cell lung cancer (NSCLC) patients treated with gemcitabine-based chemotherapy, by analyzing the immunostaining of Cav-1 and the clinical response to the chemotherapy of 73 NSCLC (stages IIIB and IV) patients.