TNF and Insulin resistance: The article “Potential roles of Stevia rebaudiana Bertoni in abrogating insulin resistance and diabetes: A review” by N. H. M.-Radzman et al. highlights the mechanisms involving free fatty acids, adipocytokines such as TNFα and PPARγ and serine kinases like JNK and IKKβ, asserted to be responsible for the development of insulin resistance.