This revealed that, though p53 tumours 1201, 1205, 1206 and 14845 exhibited small (two- to threefold) increases in copy number for regions of chromosome 6 harbouring Met and Cav1, tumours 1203 and 1204 displayed 20- and 25-fold amplifications, respectively, of a chromosomal segment spanning these two genes (Figure 8C and D and Additional file 10: Table S4). The gene discussed is TP53; the disease is neoplasm.