This association was independent of baseline clinical features including age, sex, smoking habits, BMI, HbA1c, anti-diabetic therapy, hypertension, total cholesterol, HDL cholesterol, triglycerides and hsCRP (adiponectin SD HR = 1.44, 95% CI: 1.14-1.82; p = 0.002). This evidence concerns the gene ADIPOQ and hypertensive disorder.