To establish whether mRNA levels were associated with specific diseases phenotypes, we analyzed the possible associations of genes expression with age at diagnosis, gender, smoking habit, alcohol use, presence of jaundice, diabete mellitus, family history for neoplasia, serum levels of carcinoembryonic antigen (CEA), tumor markers, tumor grading, tumor size, tumor histological type, lymph node spreading, staging of tumor, resection margins and medical therapy. The gene discussed is CEACAM5; the disease is Jaundice.