Because mutations of EGFR, KRAS, HER2, BRAF, as well as ALK fusions have been well established to be existed in lung adenocarcinoma [5], [12]–[14], these mutation and fusion genes that ‘drives’ lung adenocarcinoma were not screened in lung squamous cell carcinoma. The gene discussed is ERBB2; the disease is squamous cell lung carcinoma.