Moreover, LiverAtlas database (http://liveratlas.hupo.org.cn/) shows that SERPINA6 is a HCC significant gene and Cancer Gene Expression Database (CGED) (http://lifesciencedb.jp/cged/) suggests that this gene significantly differently expresses in HCC comparing with non-tumor liver tissues, which suggest a potential association of SERPINA6 with hepatocarcinogenesis. The gene discussed is SERPINA6; the disease is hepatocellular carcinoma.