TGFB1 and breast cancer: Of note, Zhang and colleagues have recently shown that ginsenoside 25-OCH3-PPD, isolated from Panax notoginseng and belonging to protopanaxadiols group as 20(S)-Rg3, is capable of reducing EMT markers in normoxically cultured breast cancer cells [43].Xie et al. demonstrated that ginsenoside Rg1, a major active component also isolated from Panax notoginseng but belonging to protopanaxatriol group, blocked TGFβ1-induced EMT in rat renal tubular epithelial cells [44].