Meanwhile, several studies have demonstrated that IL-17 can enhance the growth of vascular endothelial cells and influence the angiogenic progress by increasing the secretion of cytokines, such as TNF-α, IL-8, and VEGF [29], [31], including a study that reported IL-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy [32]. The gene discussed is IL17A; the disease is neoplasm.